谢晶日教授辨证治疗慢性萎缩性胃炎120例临床分析

Clinical Analysis of 120 Cases of Chronic Atrophic Gastritis Treated by Professor XIE Jing-ri

目的:观察谢晶日教授辨证治疗慢性萎缩性胃炎(CAG)的临床疗效。方法:将符合诊断标准的120例CAG患者辨证分型为肝胃气滞证、肝胃郁热证、脾胃虚弱证、脾胃湿热证、胃阴不足证、胃络瘀血证6个证型,并给予相应中药治疗,1个月后观察其中医证候疗效、胃镜疗效、各证型主要症状积分变化情况。结果:中医证候疗效方面,120例患者临床总有效率为84.17%,以肝胃气滞证临床总有效率最高,但经统计学分析比较,各型之间无明显差异(P>0.05);胃镜疗效方面,复查胃镜患者共计78例,临床总有效率为65.38%,以脾胃湿热证总有效率最高,但经统计学分析比较,各型之间无明显差异(P>0.05);主要症状积分方面,治疗后各证型主要症状积分明显低于治疗前,差异具有统计学意义(P<0.05)。结论:谢晶日教授临床辨证治疗CAG具有较好疗效,且能明显改善患者临床症状,提高患者生活质量。

Objective： To observe the clinical efficacy of chronic atrophic gastritis（ CAG） treated by professor XIE Jing-ri with TCM syndrome differentiation. Methods： 120 cases were classified into six TCM syndromes,which were qi-stagnation of liver and stomach,stagnated heat in liver and stomach,deficiency of spleen and stomach,dampness-heat of spleen and stomach,stomach-yin deficiency,and stomach blood-stasis. The patients were treated with corresponding TCM medication according to different syndromes for one month. The curative efficacy,gastroscope changes,and symptom integral were observed after the treatment. Results： The general clinical efficacy was 84. 17% of the 120 patients,of which the highest curative effect was from qi-stagnation of liver and stomach syndrome,but there were no significant difference among the six syndromes（ P〈0. 05）. For gastroscope curative effect,a total of 78 patients were re-examined with gastroscope,and the clinical total effective rate was 65. 38%,of which the highest rate is from the syndrome of dampness-heat of spleen and stomach,also there were no significant difference among syndromes（ P〈0. 05）.For symptom integral,it became significantly lower after treatment than that before treatment in each syndrome group,and the difference was statistically significant（ P〈0. 05）. Conclusion： There was a good curative effect on CAG treated by Professor XIE Jing-ri with TCM syndrome differentiation,and the medication can significantly improve clinical symptoms and improve life quality.