摘要
皮溃疡是影响病人健康和生活的质量的疾病的一种普通类型，并且细菌的感染增加细菌的文化的结果从 2011 年 1 月在我们的医院从皮溃疡的 110 个盒子的表面取样了到 2012 年 12 月的它学习收集了的在场的 management.MethodsThe 的困难。我们分析了溃疡表面细菌的成分比率，变化总体上传染的细菌和为普通细菌测试的药敏感的结果。另外，皮肤溃疡的细菌的感染的特征是 110 取样的 summarized.ResultOf， 90 个孤立的细菌是有教养的。61 是克否定的细菌，主要包括的 Pseudomonas aeruginosa， Klebsiella pneumoniae， Enterobacter 下水道和 Escherichia coli。另外， 23 孤立是克积极的细菌，主要包括的葡萄球菌 aureus 和肠球菌 faecalis。在 2012 的一种否定细菌的文化的概率在 2011 是比那显著地低的(16.7% 对 40.0% ， p ?<? 0.01 ) 。而且， P. 的概率 ? 在 2012 的 aeruginosa 感染在 2011 比那显著地高(31.7% 对 14.0% ， p ?<? 0.01 ) 。P。aeruginosa 对七通常使用的抗菌素抵抗。两 K.? pneumoniae 和 E.? coli 有更高的抵抗到氨比西林。E.? 下水道不对 piperacillin/tazobactam 敏感。Acinetobacter baumannii 对所有测试的药抵抗。S.? aureus， E。faecalis 和葡萄球菌 epidermidis 有高抵抗到 clindamycin。有另外的药抵抗反映皮肤的更高的率细菌的 resistance.ConclusionSkin 细菌的抵抗率高。克否定的细菌逐渐地说明多数，和 P。aeruginosa 成为最重要的皮肤感染病原体。皮肤溃疡的细菌的感染的这些特征为指导抗菌素的选择，更好控制皮肤溃疡的感染并且加速皮肤溃疡愈合提供一本重要参考书。
Purpose： Skin ulcer is a common type of disease affecting patients＇ health and quality of life, and bacterial infection increases the difficulty of its management. Methods： The present study collected the results of bacterial culture sampled from the surface of 110 cases of skin ulcers at our hospital from January 2011 to December 2012. We analyzed the constituent ratios of ulcer surface bacteria, the change in the main infectious bacteria and the results of drugsensitivity testing for common bacteria. In addition, the characteristics of bacterial infection of skin ulcers were summarized. Result： Of the 110 samples, 90 isolated bacteria were cultured. Sixty-one were Gram-negative bacteria, mainly comprising Pseudomonas aeruginosa, Klebsiella pneumoniae, Enterobacter cloacae and Escherichia coli. In addition, 23 isolates were Gram-positive bacteria, mainly comprising Staphylococcus aureus and Enterococcus faecalis. The probability of a negative bacterial culture in 2012 was significantly lower than that in 2011 （16.7% vs. 40.0%, p 〈 0.01）. Moreover, the probability of P. aeruginosa infection in 2012 was significantly higher than that in 2011 （31.7% vs. 14.0%, p 〈 0.01）. P. aeruginosa was resistant to seven commonly used antibiotics. Both K. pneumoniae and E. coli had higher resistance to ampicillin. E. cloacae were not sensitive to piperacillin/tazobactam. Acinetobacter baumannii was resistant to all the tested drugs. S. aureus, E. faecalis and Staphylococcus epidermidis had high resistance to clindamycin. There was other drug resistance to reflect the higher rate of skin bacterial resistance. Conclusion： Skin bacterial resistance rate is high. Gram-negative bacteria gradually account for the majority, and P. aeruginosa becomes the most important skin infection pathogen. These characteristics of bacterial infections of skin ulcers provide a significant reference for guiding the selection of antibiotics, better controlling infections of skin ulcers and accelerating the healing of skin ulcers.
