药物基因组学与临床药师

Pharmacogenomics and Clinical Pharmacists

药物基因组学是联系基因、药物和疾病间关系的一座桥梁,已逐渐成为临床药师开展临床合理用药实践的有力工具。药物基因组学在临床实践中的应用越来越广泛,通过基因检测对临床合理用药的指导作用尤为突出。通过氯吡格雷和华法林临床用药分析发现,基因分型结果能够为患者提供很好的个体化用药指导。临床药师作为临床治疗团队的成员,可充分利用自身的药学背景优势,结合相关药物基因组学信息,推动临床合理用药。

Pharmacogenomics does not only bring the connection of genes, medicines and diseases, but also become a powerful tool for clinical pharmacists. Pharmacogenomics is commonly used in clinical practice, especially in the implementation of genetic-test results for guiding rational use of medicines. The genotyping results of genes can provide good individualized medication guidance for patients, which can be confirmed by clinical use of the clopidogrel and warfarin. As a member of the clinical treatment team, clinical pharmacists should take advantage of pharmaceutical and pharmacogenomics information to promote rational use of medicines.