期刊文献+

咽喉反流和喉癌前病变 被引量:14

Laryngopharyngeal reflux disease and laryngeal precancerous lesions
原文传递
导出
摘要 咽喉反流性疾病(laryngopharyngeal reflux disease,LPRD)是胃内容物反流至食管上括约肌以上部位引起的一系列症状和体征的总称.近年来,咽喉反流(laryngopharyngeal reflux,LPR)作为喉癌前病变及喉癌的危险因素受到越来越多的关注.在喉癌发生发展的过程中,喉癌前病变是一个不容忽视的阶段.本文将就LPR在喉癌前病变发生中的作用、机制,以及抗反流在喉癌前病变治疗中的地位进行综述. The laryngopharyngeal reflux disease (LPRD) is a general term for a series of symptoms and signs caused by reflux of the stomach contents to the upper part of the esophageal sphincter.In recent years, the laryngopharyngeal reflux (LPR) is getting more and more attention as laryngeal precancerous lesions and risk factors of laryngeal cancer.Laryngeal precancerous lesions plays a important role in the development of laryngeal cancer process.This article will review the role and mechanisms of LPR in the laryngeal precancerous lesions, and the status of anti-reflux in the treatment of laryngeal precancerous lesions.
出处 《中华耳鼻咽喉头颈外科杂志》 CAS CSCD 北大核心 2017年第8期637-639,共3页 Chinese Journal of Otorhinolaryngology Head and Neck Surgery
关键词 胃食管反流 咽疾病 喉疾病 癌前状态 Gastroesophageal reflux Pharyngeal dieases Laryngeal dieases Precancerous conditions
  • 相关文献

参考文献5

二级参考文献54

  • 1冯桂建,刘玉兰.含餐3h食管pH监测和24h pH监测的比较[J].中华医学杂志,2005,85(49):3517-3518. 被引量:1
  • 2Simpson CB, Archilla AS, Velazquez RA, et al. Resolution of vocal fold leukoplakia with proton-pump inhibitor therapy. Ear Nose Throat J, 2006,85:362-364.
  • 3Williams RB, Ali GN, Wallace KL, et al. Esophagopharyngeal acid regurgitation : dual pH monitoring criteria for its detection and insights into mechanisms. Gastroenterology, 1999, 117: 1051- 1061.
  • 4Harrell SP, Koopman J, Woosley S, et al. Exclusion of pH artifacts is essential for hypopharyngeal pH monitoring. Laryngoscope, 2007,117:470-474.
  • 5Vincent DA Jr, Garrett JD, Radionoff SL, et al. The proximal probe in esophageal pH monitoring: development of a normative database. J Voice, 2000, 14:247-254.
  • 6de Vincentiis M, Gallo A, Boccia MM, et al. Environmental and occupational risk factors in keratosis of the larynx. Acta Otorhinolaryngol Ital, 1993,13:43-52.
  • 7Lenglinger J, Ringhofer C, Eisler M, et al. Histopathology of columnar-lined esophagus in patients with gastroesophageal reflux disease. Wien Klin Wochenschr, 2007,119:405-411.
  • 8Galli J, Frenguelli A, Calo L, et al. Role of gastroesophageal reflux in precancerous conditions and in squamous cell carcinoma of the larynx: our experience. Acta Otorhinolaryngol Ital, 2001, 21:350-355.
  • 9Storr M, Meining A, Allescher HD. Pathophysiology and pharmacological treatment of gastroesophageal reflux disease. Dig Dis ,2000,18:93-102.
  • 10Tokashiki R, Nakamura K, Watanabe Y, et al. The relationship between esophagoscopic findings and total acid reflux time below pH 4 and pH 5 in the upper esophagus in patients with laryngopharyngeal reflux disease (LPRD). Auris Nasus Larynx, 2005, 32:265-268.

共引文献60

同被引文献148

引证文献14

二级引证文献109

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部