摘要
支气管哮喘(bronchial asthma,简称哮喘)是一种常见的慢性气道炎症性疾病,急性发作可危及生命。研究表明,细胞因子白介素17(interleukin-17,IL-17)家族成员在哮喘的发病过程中发挥着重要的作用,其中IL-17A、IL-17F和IL-17E与哮喘密切相关,是目前的研究热点。现对IL-17家族不同成员与哮喘发病机制的相关研究进展作一综述。
Bronchial asthma is a common chronic airway inflammatory disease,which can be life-threatening as it is in an acute attack. Studies have shown the members of IL-17 family involved in the pathogenesis of asthma,and IL-17 A,IL-17 F and IL-17 E are closely related with asthma. This article reviews the research progress on the pathogenesis of asthma with different members of the IL-17 family.
出处
《微生物学免疫学进展》
2017年第4期61-64,共4页
Progress In Microbiology and Immunology
基金
国家自然科学基金(81373177
81471594)
北京市教委科技计划面上项目(KM201410025006)
关键词
白介素17A
白介素17F
白介素17E
哮喘
Interleukin-17A(IL-17A)
Interleukin-17F(IL-17F)
Interleukin-17E(IL-17E)
Asthma