摘要
自身免疫性甲状腺炎(Autoimmune thyroiditis,AIT)是典型的器官特异性自身免疫性疾病,以甲状腺内淋巴细胞浸润和特异性甲状腺自身抗体形成为特征,目前现代医学对本病缺乏有效的病因治疗,对于本病甲状腺功能正常期尚无特效药,常处于被动随访状态。中医药治疗具有多靶点、多环节、多途径特点,在防治AIT发挥特色作用。针对近年来日趋增多的中医药防治AIT的药理研究,进行系统梳理与阐述,为其进一步应用提供参考依据。
As the most common organ-specific autoimmune disease, autoimmune thyroiditis（AIT） is characterized by intrathyroidal lymphocyte infiltration and specificthyroid autoantibodies. Modern medicine is short of effective etiological treatment at present, and has no specific medicine foreuthyroidism of AIT patients, who have been followed-up passively.Chinese medicine treatmenthas the characteristics of multiple-targets, multiple-links and multiple-pathways, which plays a special superiorityrole in the prevention and treatment of AIT.The purpose of this article was to sort out and set forthmore Chinese medicine pharmacology on AIT recently, which provided evidence for further clinical apply.
出处
《世界科学技术-中医药现代化》
CSCD
2017年第5期865-869,共5页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家自然科学基金委青年基金项目(81503474):基于micro RNAs调控Th17细胞研究补气健脾法对自身免疫性甲状腺炎的干预机制,负责人:杨潇
辽宁省科技厅博士启动基金(201501110):益气化痰活血方干预自身免疫性甲状腺炎的机制,负责人:杨潇
辽宁省教育厅一般项目(L2015347):基于micro RNA探讨益气化痰活血方干预自身免疫性甲状腺炎的免疫学机制,负责人:杨潇
科学技术部国家“十二五”重大新药创制科技重大专项(2012ZX09303-017):中药新药临床评价研究技术平台,负责人:李国信
大学生创新创业训练计划项目(201510162000011):人参皂苷干预自身免疫甲状腺炎小鼠免疫机制研究,负责人:张馨心
