埃索美拉唑联合健胃愈疡片治疗反流性食管炎的安全性及有效性

Safety and Effectiveness of Esomeprazole and Jianwei Yuyang Tablets in Treatment of Relux Esophagitis

目的探讨埃索美拉唑联合健胃愈疡片治疗反流性食管炎的安全性及有效性。方法将该院100例反流性食管炎患者作为研究对象(2014年8月—2016年8月收治),随机分成2组,50例/组。观察组采取埃索美拉唑联合健胃愈疡片的治疗方案,对照组则单纯给予健胃愈疡片治疗。比较2组的症状总积分、临床疗效、不良反应情况及复发情况。结果观察组治疗后的症状总积分(5.12±0.41)分和复发率(2.00%)均低于对照组(P<0.05),治疗总有效率(98.00%)比对照组高(P<0.05),2组的不良反应无明显差别(对照组:6.00%,观察组:8.00%)(P>0.05)。结论埃索美拉唑联合健胃愈疡片治疗反流性食管炎安全有效。

Objective To study the safety and effectiveness of esomeprazole and jianwei yuyang tablets in treatment of relux esophagitis. Methods 100 cases of patients with relux esophagitis in our hospital from August 2014 to August 2016 were selected and randomly divided into two groups with 50 cases in each, the observation group were treated with esomeprazole and jianwei yuyang tablets, while the control group were treated with simple jianwei yuyang tablets, and the total integral of symptoms, clinical curative effect, adverse reaction and recurrence situation were compared be- tween the two groups. Results After treatment, the total integral of symptoms and recurrence rate in the observation group were lower than those in the control group, which were respectively （5.12±0.41）marks and 2.00% （P〈0.05）, and the total effective rate （98.00%）was higher than that in the control group（P〈0.05）, and there were no obvious adverse reactions between the two groups （in the control group; 6.00%, in the observation group： 8.00%）（P〉0.05）. Conclusion The esomeprazole and jianwei yuyang tablets in treatment of relux esophagitis is effective.