胺碘酮联合美托洛尔静脉注射治疗快速心律失常的临床分析

Analysis of Amiodarone and Metoprolol in the Venous Injection Treatment of Tachyarrhythmia

目的评价胺碘酮联合美托洛尔静脉注射治疗快速心律失常的近远期疗效。方法 2015年2月—2016年6月,以内蒙古自治区巴彦淖尔市医院心血管内科选择胺碘酮治疗患者作为研究对象,40例纳入胺碘酮组,选择胺碘酮+美托洛尔治疗患者54例,纳入联合组;对比治疗前、24 h后指标变化,临床疗效。结果联合组总有效率100.00%高于胺碘酮组85.00%,联合组无效率0.00%低于胺碘酮组15.00%,差异有统计学意义(P<0.05);24 h后,组内对比联合组与胺碘酮组SBP、DBP、HR低于治疗前,组间对比联合组低于胺碘酮组,组内对比联合组与胺碘酮组E/A高于治疗前、联合组高于胺碘酮组,差异有统计学意义(P<0.05)。结论胺碘酮联合美托洛尔静脉注射治疗快速心律失常疗效肯定。

Objective To evaluate the long-term and short-term curative effect of amiodarone and metoprolol in the venous injection treatment of tachyarrhythmia. Methods 40 cases of patients with amiodarone treatment in our hospital from February 2015 to June 2016 were selected as the amiodarone group, and 54 cases of patients with amiodarone and metoprolol were selected as the combined group, and the index change and clinical curative effect before treatment and 24 h after treatment＇ were compared. Results The total effective rate in the combined group was higher than that in the amiodarone group（100.00% vs 85.00%）, The inefficiency of the combined group was 0.00% lower than that of the amiodarone group 15.00%,and the difference had statistical significance （P〈0.05）, after 24 h, the SBP, DBP and HR of the two groups were lower than those before treatment, and the SBP, DBP and HR in the combined group were lower than those in the amiodarone group, and the E/A of the two groups was obviously higher than that before treatment, and the E/A in the combined group was higher than that in the amiodarone group （P〈0.05）. Conclusion The curative effect of amiodarone and metoprolol in the venous injection treatment of tachyarrhythmia is positive.