hs-CRP与WBC联合检测在儿童上呼吸道感染中的应用

Application of Combined Test of hs-CRP and WBC in the Upper Respiratory Tract Infection in Children

目的探讨hs-CRP与WBC联合检测在儿童上呼吸道感染诊断中的作用。方法选取2013年12月—2015年12月在长春市儿童医院检验科进行检测的上呼吸道感染患儿158例作为观察组,选取同期健康儿童158名作为对照组,比较两组hs-CRP与WBC之间的差异和阳性率。结果观察组(细菌感染)hs-CRP值为(59.5±24.8)mg/L,WBC值为(15.6±4.3)×10~9/L;对照组hs-CRP值为(2.3±0.5)mg/L,WBC值为(6.2±1.3)×10~9/L,两组相比差异有统计学意义(P<0.05);观察组(病毒感染)hs-CRP值为(2.1±0.5)mg/L,WBC值为(6.8±2.6)×10~9/L,与对照组相比差异无统计学意义(P>0.05)。观察组(细菌感染)hs-CRP阳性率为51.4%,WBC阳性率为32.9%,观察组(病毒感染)hs-CRP阳性率为0.0%,WBC阳性率为0.0%,对照组hs-CRP阳性率为0.0%,WBC阳性率为0.0%。观察组(细菌感染)与对照组相比差异有统计学意义(P<0.05),观察组(病毒感染)与对照组相比差异无统计学意义(P>0.05)。结论 hs-CRP与WBC联合检测在诊断细菌性儿童上呼吸道感染中意义重大,值得应用。

Objective To discuss the effect of combined test of hs-CRP and WBC in the upper respiratory tract infection in children. Methods 158 cases of children with upper respiratory tract infection in our hospital from December 2013 to December 2015 were selected as the observation group, while 158 cases of healthy children at the same period were selected as the control group, and the differences and positive rate of hs-CRP and WBC of the two groups were compared. Results The differences in the hs-CRP value （virus infection） and WBC value between the observation group and the control group had statistical significance[（59.5±24.8）mg/L, （15.6±4.3）×10^9/L vs （2.3±0.5）mg/L, （6.2±1.3）× 10^9/L]（P〈0.05）, and the hs-CRP value （virus infection） and WBC value in the observation group were respectively （2.1±0.5）mg/L and （6.8±2.6）×10^9/L , and the differences between the two groups had no statistical significance （P〉 0.05 ）. The hs-CRP positive rate （bacterial infection） and WBC positive rate in the observation group was respectively 51.4% and 32.9%, and the hs-CRP positive rate （virus infection） and WBC positive rate was respectively 0.0% and 0.0% in both groups, and the difference in the hs-CRP positive rate （bacterial infection） and WBC positive rate between the two groups had statistical significance（P〈0.05）, but the difference in the hs-CRP positive rate （virus infection） and WBC positive rate had no statistical significance（P〉0.05）. Conclusion The significance of combined test of hs-CRP and WBC in the upper respiratory tract infection in children is significant, which is worth application.