重症急性胰腺炎的液体复苏与器官保护

Fluid resuscitation and organ protection in the treatment of severe acute pancreatitis

重症急性胰腺炎(SAP)的发病率逐年增高,并且起病凶险,致残率、病死率高。重症急性胰腺炎的治疗是一种涉及多个学科,多种手段的综合治疗。不同的学科从不同的角度,有着不同的治疗理念,并且对疾病不同阶段的认识也不同。但在其非手术治疗手段中,有效的液体复苏与脏器保护对降低重症急性胰腺炎的病死率起到非常重要的作用。本文从重症医学的角度,归纳总结了在重症急性胰腺炎治疗过程中,液体复苏治疗及器官保护治疗的最新理念及治疗进展。以及对目前的治疗方法中,存在的问题进行了进一步的剖析。

Incidence of severe acute pancreatitis（SAP） was increased in recent years,with severe clinical outcome,high morbidity and mortality. The comprehensive treatment of severe acute pancreatitis required multiple disciplines by a variety of means. Different disciplines have their own treatment concepts based on different perspectives and understanding of different stages of this disease. However,in conserved treatment,fluid resuscitation and organ protection treatment could significantly reduce the mortality of severe acute pancreatitis. In this paper,from the perspective of severe medicine,we reviewed the latest concepts and progress of liquid resuscitation therapy and organ protection in the treatment of severe acute pancreatitis,as well as the problems of current treatment,which still need further investigation.