坤宁益寐汤治疗女性更年期不寐76例

Treating 76 Female Patients with Menopausal Insomnia by KunNing YiMei Tang

目的:观察坤宁益寐汤治疗女性更年期不寐的临床疗效。方法:将129例患者随机分为2组,治疗组76例采用坤宁益寐汤为基本方辨证施药,对照组53例口服安定片,2组均连续治疗20天。结果:观察组痊愈率为73.7%,总有效率为94.7%;对照组痊愈率为35.8%,总有效率为88.7%。观察组临床疗效优于对照组,差异有统计学意义(P<0.05)。睡眠质量2组治疗后均明显改善(P<0.05),观察组改善更明显(P<0.05)。观察组有4例服中药后出现轻度纳差、恶心、头晕等反应,对照组有26例产生药物依赖。结论:坤宁益寐汤治疗妇女更年期不寐具有较好的临床疗效,且无药物依赖之虑。

Objective： To observe clinical effects of KunNing YiMei Tang in treating female patients with menopausal insomnia. Methods： All 129 patients were randomized into two groups, 76 cases of the treatment group adopted KunNing YiMei Tang as basic prescription and performed syndrome differentiation and herbs. 53 cases of the control group took diazapam tablets, both groups were treated for 20 days consecutively. Results： Cure rate of the observation group was 73.7%, and total effective rate 94.7%; cure rate of the control group was 35.8% and total effective rate 88.7%. The observation group was superior to the control group in clinical effects, and the difference showed statistical meaning （P〈0.05）. Sleeping quality of both groups was improved notably after treating （P〈0.05）, and the improvements of the observation group were more obvious （P〈0.05）. There were four cases showing light poor appetite, nausea, vertigo after taking the medicine in the observation group, 26 cases with drug dependence in the control group. Conclusion： KunNing YiMei Tang is effective in treating female patients with menopausal insomnia, and free to drug dependence.