影响动脉瘤性蛛网膜下腔出血合并慢性脑积水的危险因素分析

Risk factors analysis on aneurysmal subarachnoid hemonhage complication with chronic hydrocephalus

目的:探讨动脉瘤性蛛网膜下腔出血(a SAH)合并慢性脑积水的相关危险因素。方法:采用回顾性病例对照法,以确诊的a SAH合并慢性脑积水为病例组,同时以50例未发生脑积水的a SAH病例作为对照组,采用单因素比较分析和多因素Logistic回归法来筛选a SAH合并慢性脑积水的相关危险因素。结果:多因素分析结果显示,影响a SAH合并慢性脑积水的因素包括年龄(OR=2.866)、高血压病史(OR=5.197)、出血破入脑室(OR=3.702)、出血次数(OR=2.606)及Hunt-Hess分级(OR=2.145)。结论:a SAH合并慢性脑积水的独立高危因素包括高龄、高血压病史、出血破入脑室、多次出血、Hunt-Hess分级高等,应针对这些高危因素采取必要的干预措施。

[ Objective] To explore the risk factors of aneurysmal subarachnoid hemonhage complication with chronic hydro- cephalus （aSAH）. [ Melhod] With retrospective case- control study method, 50 cases of aSAH complication with chronic hy- drocephalus were chose as case group, and another 50 cases of aSAH without chronic hydrocephalus were chose as control group. Then, single comparison between the two groups and multiple factors Logistic Regression method were used to screen correlated risk factors of aSAH complication with chronic hydrocephalus. [ Result] Multiple factors analysis result showed that age （ OR = 2.866 ）, history of hypertension （OR = 5.197）, hemorrhage into the ventricles of the brain （OR = 3.702 ）, times of hemorrhage （OR = 2.606）, grading of Hunt- Hess （OR = 2. 145） were the influencing factors of aSAH complication with chronic hydrocephalus. [ Conclusion] The high risk factors of aSAH complication with chronic hydrocephalus include in high age, history of hypertension, multiple hemorrhage and high grading of Hunt- Hess. We should adopt intervention measures to aim directly at these high risk factors.