针刺联合康复训练治疗小儿脑瘫的疗效观察及对脑血流的影响

Clinical effect and influence on cerebral blood flow of children with cerebral palsy treated with acupuncture combined rehabilitation training

目的观察针刺联合康复训练治疗小儿脑瘫的临床疗效及对患儿肢体运动功能和脑血流的影响。方法将2011年4月至2016年8月于我院针灸科就诊的81例脑瘫患儿随机分为对照组40例和治疗组41例,对照组采用康复训练治疗,治疗组在康复训练的基础上联合针刺治疗,2组均以3月为1个疗程,1个疗程后比较2组患儿的临床疗效。结果治疗后2组粗大运动功能评估(GMFM)评分显著升高,肌张力评分显著下降,与同组治疗前比较,差异均有统计学意义(P<0.05),且治疗组改善幅度大于对照组(P<0.05);治疗后2组大脑动脉血流速度(VP)显著增加,血管内皮生长因子(VEGF)水平显著下降,与同组治疗前比较,差异均有统计学意义(P<0.05),且治疗组改善幅度大于对照组(P<0.05);对照组总有效率为75.00%,治疗组为92.68%,2组总有效率经统计学分析,差异有统计学意义(P<0.05)。结论针刺联合康复训练治疗小儿脑瘫疗效显著,可更好地改善肢体运动功能和脑部血流速度,值得在临床上推广。

Objective To investigate the clinical effect of acupuncture combined with rehabilitation training on children with cerebral palsy and children＇ s limb movement and cerebral blood flow. Methods 81 cases with cere- bral palsy from April,2011 to August,2016 in our hospital were randomly divided into two groups. Control group with 40 cases were treated with modem rehabilitation training treatment, and therapy group with 41 cases was given acupuncture based on the therapy of control group,3 months a course for both groups. Clinical effect of two groups was observed and compared after one course. Results After the treatment, GMFM leveis were increased in two groups, but the muscle tension score was lower, there were significant differences comparing these before treatment （P〈0. 05 ）, while the therapy group improved more significantly （ P〈0.05 ） ; levels of VEGF, VP were higher than before, but the therapy group improved more significantly （ P〈0.05 ） ; the total effective rate of the control group was 75.00%, and that of the therapy group was 92.68 % with significant difference （P〈0.05）. Conclusion Acupunc- ture combined with rehabilitation training can treat children with cerebral palsy effectively and significantly by im- proving limb movement function and brain blood flow velocity ,which is worth promoting.