血栓通联合奥扎格雷钠治疗急性脑梗死的临床疗效

Clinical effect of Xueshuantong combined with sodium ozagrel in the treatment of acute cerebral infarction and the effect on nerve function

目的探讨血栓通联合奥扎格雷钠治疗急性脑梗死的临床疗效。方法选择134例急性脑梗死患者,随机分为对照组和研究组,各67例。对照组在常规治疗基础上应用奥扎格雷钠治疗,研究组在对照组治疗的基础上加用血栓通注射液治疗,治疗后观察患者的疗效及神经功能缺失评分(NIHSS)的变化。结果对照组治疗前的NIHSS评分为(23.38±4.73)分,研究组治疗前的NIHSS评分为(23.60±4.46)分,两组的NIHSS评分在治疗前比较,无统计学意义(P<0.05),对照组治疗后的NIHSS评分为(15.60±3.85)分,研究组治疗后的NIHSS评分为(10.27±3.04)分,两组的NIHSS评分在治疗后比较,研究组优于对照组,差异有统计学意义(P<0.05)。治疗后对照组有效率为83.6%,研究组的有效率为95.5%,两组治疗后总有效率比较,研究组优于对照组,差异有统计学意义(P<0.05)。结论血栓通联合奥扎格雷钠治疗急性脑梗死可促进神经功能恢复,提高临床疗效,值得在临床应用。

Objective To explore the clinical effect of Xueshuantong combined with sodium ozagrel in the treatment of acute cerebral infarction.Methods 134 cases of acute cerebral infarction were randomly divided into control group and study group with 67 cases in each group. The control group received sodium ozagrel on the basis of conventional therapy for the treatment. The study group was treated with Xueshuantong injection combined with sodium ozagrel. The efficacy and the change of NIHSS of the two groups were observed.Results The NIHSS scores of control group and study group before treatment were 23.38±4.73 and 23.38±4.73 respectively, the difference between the two groups was not statistically significant （P〉0.05）. After treatment, NIHSS of the two groups were 15.60±3.85 and 10.27±3.04 respectively, the difference was statistically significant （P〈0.05）. The effective rate of control group was 83.6%, and it was 95.5% in study group, the study group was higher than the control group （P〈 0. 05 ）. Conclusions The combination of Xueshuantong and sodium ozagrel can promote the recovery of neurological function in the treatment of acute cerebral infarction, improve the therapeutic effect, worth of clinical application.