《当代名医临证精华·消渴专辑》治疗消渴病组方用药规律分析

The Prescription Law of Diabetes Formula from Contemporary Distinguished Physician Medical Cases Diabetes Section

目的 :探讨当代名医治疗消渴病的临床用药规律,为临床治疗该病证提供参考。方法 :查阅《当代名医临证精华·消渴专辑》中33位当代名医治疗消渴病的经验方,将复方中涉及到的单味药建立EXCEL 2003用药数据库,运用频数分析法以及聚类分析对用药规律进行统计学分析。结果:共筛选出93首复方,共涉及药物150味,用药频次达1 059次,其中用药频次大于30次的分别为山药、黄芪、生地黄、茯苓、天花粉、麦冬、党参。按照中药类别分析,用药总频次最多的类别为补虚药,其次为清热药和利水渗湿药。聚类分析结果显示清热生津药、补益脾气药、滋补肝肾药是临床治疗消渴病的常用配伍。结论:近代名医治疗消渴病主要以补虚、清热、利水渗湿为主,运用聚类分析法对治疗消渴病的药物进行统计分析,能在一定程度上揭示组方规律,为临床治疗提供参考。

Objective：To explore the prescription law of contemporary distinguished physician treating diabetes and provide a references for treating diabetes. Methods：There were experience formulas by the 33 contemporary distinguished physicians were analyzed from Contemporary Distinguished Physician Medical Cases Diabetes Section,and the involved herbs were input into a database using Excel software. Frequency analysis and cluster analysis were applied to analyze the prescription law. Results：There were 93 formulas selected involving 150 herbs,with medication frequency of 1 059,in which the medication frequency of Shanyao, Huangqi,Shengdihuang,Fuling,Tianhuafen,Maidong and Dangshen was more than 30 times. According to the herbal category,herbs for tonifying with the highest frequency followed by for clearing heat and inducing diuresis and excreting dampness. Cluster analysis results showed that the herbs for clearing and generating fluids,tonifying spleen qi,nourishing the liver and kidneys were the commonest combination. Conclusion：The treatment for diabetes by contemporary distinguished doctors mainly involves tonifying the deficiency,clearing heat and inducing diuresis and excreting dampness. By cluster analysis on the herbs for diabetes,the prescription law can be determined and to provide a reference for clinical treatment.