摘要
目的 :探究通窍鼻炎丸对慢性鼻窦炎患者体内相关炎性因子的影响。方法 :采用酶联免疫法(ELISA法)检测通窍鼻炎丸治疗慢性鼻窦炎患者前后血清中IL-1β、IL-5及TNF-a含量变化,并与克拉霉素对照组及空白组进行比较。结果:通窍鼻炎丸治疗慢性鼻窦炎患者血清中IL-1β、IL-5及TNF-a含量明显低于克拉霉素对照组,差异具有统计学意义(P<0.01)。结论:通窍鼻炎丸能明显降低慢性鼻窦炎患者体内相关炎性因子IL-1β、IL-5及TNF-a的含量,对治疗慢性鼻窦炎有一定临床效果。
Objective：To study the effects of Tongqiao Biyan pill on the body of patients with chronic sinusi- tis related inflammatory factors. Methods：Using enzyme-linked immunosorbent assay （ELISA） detected serum IL-1β,IL-5 and TNF-a content changes before and after treated by Tongqiao Biyan pill in chronic sinusitis patients,and compared with the control of clarithromycin and blank group. Results：The serum Tongqiao Biyan pill in the treatment of patients with chronic sinusitis in IL-1β,IL-5 and TNF-a were significantly lower than the clarithromycin control group ,the difference was statistically significant（P〈0.01 ）. Conclusion： Tongqiao Biyan pill can lower in patients with chronic sinusitis related inflammatory cytokine of content of IL-1β,IL-5 and TNF-a,has important clinical significance to the treatment of chronic sinusitis.
出处
《山东中医杂志》
2017年第8期663-665,共3页
Shandong Journal of Traditional Chinese Medicine
基金
甘肃省中医药管理局课题(编号:GZK-2016-38)
