骨髓坏死治疗研究进展

Research Progress of the Treatment of Bone Marrow Necrosis

骨髓坏死是指造血骨髓中组织和基质的大片坏死,是一个少见的临床综合征。骨髓坏死不是独立的疾病,而是诸多疾病的共同病理变化,多发于各种实体性肿瘤、恶性血液病等,也可见于重症感染、败血症等,一旦发生骨髓坏死常提示预后不良。全文就近年来骨髓坏死的临床特征、实验室检查及治疗进展作一综述。

Bone marrow necrosis is a rare clinical syndrome which is characterized by massive necrosis of tissues and stroma in bone marrow（BMN）. It is not an independent disease,but a common pathological change of many diseases. It is more common in variety of solid tumors and malignant blood disease. It can also be found in severe infection,septicemia,et al. BMN often indicates a poor prognosis. This article reviews the clinical features,laboratory examination and treatment research progress of bone marrow necrosis.