银杏达莫注射液联合替罗非班治疗非ST段抬高型急性冠状动脉综合征的疗效观察

Efficacy of yinxingdamo injection combined with tirofiban for non ST segment elevation acute coronary syndrome

目的 探讨银杏达莫注射液联合替罗非班治疗非ST段抬高型急性冠状动脉综合征（NEST-ACS）的临床疗效.方法 选择86例NEST-ACS患者作为研究对象,将其平均分为观察组和对照组.对照组给予替罗非班治疗,观察组在对照组基础给予银杏达莫注射液.评价两组疗效;治疗前后,检测两组患者血流变指标（高切全血黏度、血浆黏度、红细胞压积、红细胞聚集指数及红细胞变形指数）水平和左心功能相关指标[心输出量（CO）、每搏输出量（SV）、心脏左室舒张内径（LVDD）及射血分数（LVEF）]水平.结果 治疗后,观察组总有效率明显高于对照组（P〈0.05）.治疗后,观察组血流变指标及左心功能相关指标改善程度均明显优于对照组（P〈0.05）.结论 银杏达莫注射液联合替罗非班治疗NEST-ACS疗效较好,值得进一步研究.

Objective To investigate the effects of yinxingdamo injection combined with tirofiban on non ST segment elevation acute coronary syndrome.Methods Eighty-six non ST segment elevation elevation acute coronary syndrome patients were divided into the control group and treatment group.The control group was given tirofiban, on the basis of control group, the treatment group was given yinxingdamo injection.The effects of two groups were compared.The levels of blood rheology indexes （high shear whole blood viscosity, plasma viscosity, erythrocyte deposited, erythrocyte aggregation index and erythrocyte deformation index） and left ventricular function indicators （CO, SV, LVDD and LVEF） were detected.Results The total effective rate in the treatment group were significantly higher than that in the control group （P〈0.05）.After treatment, the levels of blood rheology indexes and left ventricular function indicators were significantly promoted in the treatment group than those in the control group （P〈0.05）.Conclusions The effect of yinxingdamo injection combined with tirofiban on non ST segment elevation acute coronary syndrome is good.