内镜联合腹腔镜治疗重症急性胰腺炎并发胰腺假囊肿的疗效观察

Clinical observation of endoscopic combined with laparoscopic in the treatment of severe acute pancreatitis and pancreatic pseudocyst

目的探讨内镜联合腹腔镜治疗重症急性胰腺炎并发胰腺假性囊肿的临床效果。方法选取重症急性胰腺炎并发胰腺假囊肿患者82例，按照入院先后顺序分为对照组和观察组。对照组行传统开腹手术治疗，观察组采用内镜联合腹腔镜进行治疗，观察分析两组手术情况、术后机体炎症反应程度及其并发症发生情况。结果观察组手术时间、术中出血量、排气时间及住院时间均明显优于对照组，差异有统计学意义（P〈0．05）；观察组术后白细胞介素-6、白细胞介素-8及肿瘤坏死因子一仅水平均明显低于对照组，差异有统计学意义（P〈0．05）。结论采用内镜联合腹腔镜治疗重症急性胰腺炎并发胰腺假囊肿，可有效减少手术创伤，有利于促进机体炎症反应的缓解及患者术后及早恢复，建议在临床进一步推广。

Objective To investigate the clinical effect of endoscopic combined with laparoscopy on severe acute pancreatitis and pancreatic pseudocyst. Methods A total of 82 patients with severe acute pancreatitis and pancreatic pseudocyst were selected and divided into control group and observation group according to the order of admission. The patients in control group received traditional open Abdominal surgery, and the patients in observation group were treated by endoscopic combined with laparoscopy. The surgery, postoperative inflammatory response and the incidences of complications were observed and analyzed between the two groups. Results The levels of IL-6, IL-8 and TNF-α in the observation group were significantly higher than those in the control group （ P 〈 0.05 ）. The operation time, the amount of blood loss, the exhaust time and the hospitalization time of the observation group were significantly better than those of the control group, the differences were significant （P 〈 0. 05 ）. Conclusions Endoscopic combined with laparoscopic in the treatment of severe acute pancreatitis and pancreatic pseudocysts, can effectively reduce the surgical trauma, help to promote the relief of the body＇ s inflammatory response and early recovery after surgery, it is recommended to further promote the clinical.