精神分裂症与双相情感障碍患者的认知功能分析

Analysis of cognitive function in schizophrenia and bipolar disorder

目的探讨精神分裂症与双相情感障碍患者的认知功能。方法选择本院2015年4月-2016年6月收治的60例精神分裂症患者作为对照组,60例双相情感障碍患者作为研究组,通过对两组患者进行MATRICS共识认知成套测验(MCCB)进行认知功能检测,主要包括语言能力与操作能力的测试。结果 (1)两组患者的语言能力比较:通过比较后发现,研究患者中言语记忆、言语流畅、视觉记忆、情绪管理、迷宫等各项评分明显高于对照组,差异具有统计学意义(P<0.05);研究组患者语言能力总分明显高于对照组,差异具有统计学意义(P<0.05);(2)两组患者操作能力比较:通过比较后发现,研究患者中连线、空间广度、符号编码、持续操作、数字序列等各项评分明显高于对照组,差异具有统计学意义(P<0.05);研究组患者操作能力总分明显高于对照组,差异具有统计学意义(P<0.05)。结论精神分裂症与双相情感障碍的患者通过MCCB测试能有效的反映出认知功能的差异。

Objective To analyze the cognitive function of schizophrenia and bipolar disorder. Methods 60 cases of schizophrenia patients admitted in our hospital from April 2015 to June 2016 were chosen as control group, 60 cases of patients with bipolar disorder were chosen as study group. Two groups were given MATRICS consensus cognitive test battery （MCCB） cognitive function test, including language ability and operation ability test. Results （1） Language ability between two groups were compared： According to results, verbal memory, verbal fluency, visual memory, emotion management and maze scores in experimental group were significantly higher than those in the control group, the difference was statistically significant （P〈0.05）; Score of language ability in study group were significantly higher than that in control group with statistically significant difference （P〈0.05）; （2） Operation ability between two groups were compared, and results showed that studied line, spatial span, symbol encoding, continuous operation and the digital sequence score in expermental group were significantly higher than those in control group, the difference was statistically significant （P〈0.05） ; Score of operation ability in experimental group was significantly higher than that in control group. The difference was statistically significant （P〈0. 05 ）. Conclusion MCCB test can effectively reflect the difference of cognitive function between patients with schizophrenia and bipolar disorder.