玫瑰痤疮与皮肤屏障

Rosacea and Skin Barrier

玫瑰痤疮是一种病因复杂的慢性炎症性疾病,主要与血管舒缩功能、神经血管调节功能、免疫功能等有关。近年来,越来越多的研究表明,玫瑰痤疮的发生、发展与皮肤屏障功能的受损有密切的联系,而修复皮肤屏障的治疗同时可明显缓解玫瑰痤疮患者干燥、瘙痒、刺痛、阵发性潮红等临床症状。这个特点使得皮肤屏障功能的研究在玫瑰痤疮的研究中越来越受到重视,皮肤屏障功能的研究也为玫瑰痤疮的发病机制及治疗提供了新的思路。

Rosacea is a chronic inflammatory disease. The causes of rosacea are quite complicated, mainly related to vasomotor disturbance, neurovascular regulation and immune function. In recent years, more and more studies have demonstrated that the onset and development of rosacea are closely related to skin barrier dysfunction. Moreover, the recovery of skin barrier can significantly relieve the dryness ,itching,burning ,flushing and other clinical symptoms of rosacea patients. The association between rosacea and skin barrier has attraced more and more attention. The study of skin barrier function can also provide new ideas for the study of pathogenesis and treatment of rosacea.