摘要
背景术后不良反应至今仍无较好的防治策略；甲强龙是。肾上腺糖皮质激素类药物，具有抗炎、免疫抑制、抗休克等作用，目前主要应用于严重感染、自身免疫性疾病及抗休克治疗；现在越来越多的麻醉医师在围手术期应用甲强龙管理术后恶心呕吐（postoperative nausea and vomiting, PONV）、疼痛、维持气道稳定和减轻炎症反应等。目的为临床围手术期应用甲强龙预防术后副作用提供临床参考。内容综述甲强龙对PONV、疼痛、气道稳定和炎症反应等的影响。趋向甲强龙联合用药在临床麻醉应用中具有广阔前景。
Background There is still no good prevention strategy about postoperative adverse reactions. Methylprednisolone is one kind of glucocorticoid drug with anti-inflammatory, immunosuppressive, and anti-shock effects. Now more and more anesthesiologists use methylprednisolone treat postoperative adverse reactions such as postoperative nausea and vomiting （PONV）, pain, airway stability and inflammatory reactions. Objective To provide the clinical reference for clinical application of methylprednisolone in the perioperative period. Content This review summarized the influence of methylprednisolone on PONV, pain, airway stability and inflammatory reactions. Trend Methylprednisolone combined with other drugs have broad prospects in clinical anesthesia application.
出处
《国际麻醉学与复苏杂志》
CAS
2017年第8期731-735,共5页
International Journal of Anesthesiology and Resuscitation
基金
辽宁省自然科学基金（2014021023）
关键词
甲强龙
临床麻醉
围手术期
Methylprednisolone
Clinical anesthesia
Perioperative period
