微创外科治疗局限性鼻咽癌微小浸润灶的疗效分析

Effects of minimally invasive surgical treatment of localized nasopharyngeal carcinoma

目的:研究微创外科治疗局限性鼻咽癌微小浸润灶的疗效。方法:研究对象选取我院2013年6月到2015年6月间收治的局限性残留或复发鼻咽癌患者25例,均行鼻内镜下鼻咽切除术治疗,对鼻咽肿瘤周边安全边缘区域实施连续、整块切除。统计所有患者的标本体积、肿瘤体积、手术时间、术中出血量、住院时间等资料,同时统计术后并发症及术后1年生存率。结果:所有患者的平均手术时间为(237.26±41.93)min,平均出血量为(143.90±52.13)ml,平均住院时间为(5.41±1.89)天,术后复发率为4.00%,术后并发症发生率为12.00%,术后1年生存率达100.0%。结论:鼻内镜引导下鼻咽切除术具有广泛的手术视野,能彻底切除鼻咽残留和复发病灶,且术后并发症低,术后1年生存率较高,值得在临床推广。

Objective： To study the effect of minimally invasive surgery for nasopharyngeal carcinoma micro invasive foci limitations. Methods： Twenty five localized residual or recurrent nasopharyngeal carcinoma patients in our hospital from June 2013 to June 2015 underwent endoscopic sinus surgery,continuous,en bloc resection of nasopharyngeal tumor peripheral edge was implemented in the secured area. Tumor sample volume,tumor volume,operation time,intraoperative blood loss,hospitalization time and other data,postoperative complications and postoperative 1 year survival rate were analyzed. Results： The average operation time was（ 237. 26 ＋ 41. 93） Min,the average amount of bleeding was（ 143. 90 ＋ 52. 13） ml,the average hospitalization time was（ 5. 41 ＋ 1. 89）days,the recurrence rate was 4%,the incidence of postoperative complications was 12%,postoperative 1 year survival rate was 100. 0%. Conclusion： Endoscopic guide nasopharyngeal resection has wide surgical field,capable of complete resection of nasopharyngeal residual and recurrent lesions, low complications and high postoperative 1 years survival rat,thus it is worthy of clinical application.