综合护理干预对垂体瘤假包膜囊外切除患者应激反应指标及炎症指标的影响

Effect of comprehensive nursing intervention on stress response index and inflammatory index in patients with pituitary tumor

目的:探究与分析综合护理干预对垂体瘤假包膜囊外切除患者应激反应指标及炎症指标的影响。方法:选取我院自2014年6月至2016年6月收治的90例垂体瘤假包膜囊外切除患者,采取随机数字表法分为对照组与观察组,每组各45例,对照组给予常规护理,观察组给予综合护理干预,对比两组应激反应指标、炎症指标及生活质量。结果:对照组手术后与手术前相比HR、SBP及RPP均升高,对照组手术后与观察组手术后相比HR、SBP及RPP均较高,观察组手术后与对照组手术相比HR、SBP及RPP改变的幅度较低,差异具有统计学意义(P<0.05)。两组手术后与手术前相比IL-6、IL-8及IL-10水平降低,观察组手术后与对照组手术后相比IL-6、IL-8及IL-10水平降低更加显著,差异具有统计学意义(P<0.05)。观察组与对照组相比角色功能、躯体功能、心理功能、社会功能评分均较高,差异具有统计学意义(P<0.05)。结论:对垂体瘤假包膜囊外切除患者实施综合护理干预,能够降低应激反应及炎症反应,提高患者术后生活质量。

Objective： To explore and analyze the effect of comprehensive nursing intervention on stress reaction index and inflammatory index in patients with pituitary adenoma. Methods： Ninety cases of pituitary tumor pseudocapsule sac in our hospital from June 2014 to June 2016 were randomly divided into control group and observation group,45 cases in each. The control group was given routine nursing,the observation group received nursing intervention. Their quality index and inflammatory response of life index were compared. Results： HR,SBP and RPP were increased in the control group after surgery,they were increased compared the observation group after surgery,the difference was statistically significant（ P〈0. 05）. IL-6,IL-8 and IL-10 decreased in the two groups after surgery,they decreased more significantly in the observation group compared with those in the control group after surgery,the difference was statistically significant（ P〈0. 05）. The role function,physical function,psychological function and social function score were higher in the observation group than those in the control group,and the difference was statistically significant（ P〈0. 05）. Conclusion： Comprehensive nursing intervention can reduce the stress reaction and the inflammatory reaction,and improve the quality of life of the patients with pituitary tumor.