升降浮沉药性理论溯源及升降浮沉药对配伍研究

Origin of lifting and lowering theory and its herb pair study

升降浮沉药性理论是指导临床组方遣药的重要依据之一。通过古籍及文献研究得知,升降浮沉理论萌芽于《黄帝内经》,实践于《伤寒杂病论》,成立于《医学启源》,发展于《本草纲目》及现代。升降浮沉理论目前大多停留在理论研究阶段,实验研究少有,临床研究中其对组方的指导主要包括升降相反、升降相生、以升为主和以降为主4种形式。运用升降浮沉药性配伍的药对主要有升药配对、升降配对和降药配对3种。利用现代生物学技术开展升降浮沉药性实验研究,揭示升降浮沉的科学内涵,将有助于其更科学的指导临床用药。

Lifting and lowering theory is one of the important basis for guiding clinical medication. Through the study of ancient books and literature,we learned that lifting and lowering theory was originated in Huangdi Neijing,practiced more in the Shanghan Zabing Lun,established in Yixue Qiyuan,and developed in Compendium of Materia Medica and now. However,lifting and lowering theory is now mostly stagnated in the theoretical stage,with few experimental research. In the clinical study,the guiding role of lifting and lowering theory to prescriptions mainly includes opposite role of lift and lower medicine property,mutual promotion of lift and lower medicine property,main role of lift medicine property and main role of lower medicine property. Under the guidance of lifting and lowering theory,the herb pair compatibility include herb combination of lift medicine property,herb combination of lift and lower medicine property and herb combination of lower medicine property. Modern biological technology was used in this study to carry out experimental research on the lifting and lowering theory,revealing the scientific connotation of it,which will help to promote clinical rational drug use.