应用速度向量成像技术评价主动脉瓣狭窄早期病人左心室心肌收缩功能

ASSESSMENT OF LEFT VENTRICULAR SYSTOLIC FUNCTION IN PATIENTS WITH AORTIC STENOSIS BY VELOCITY VECTOR IMAGING

目的应用速度向量成像技术(VVI)检测主动脉瓣狭窄早期病人的左心室纵向和径向应变、应变率,了解其变化规律。方法左心室射血分数正常的主动脉瓣狭窄病人55例,根据主动脉瓣狭窄程度分为轻度组25例、中-重度组30例,应用VVI分别测量左心室整体收缩期纵向峰值应变(GLPSS)及其峰值应变率(GLPSSr)、左心室整体收缩期径向峰值应变(GRPSS)及其峰值应变率(GRPSSr)。以性别和年龄匹配的健康志愿者25例作为对照组。结果与对照组比较,轻度组GLPSS、GLPSSr减低,中-重度组GLPSS、GLPSSr、GRPSS、GRPSSr均明显减低,差异有统计学意义(F=4.25~42.52,P<0.01);轻度组GRPSS、GRPSSr差异无显著性(P>0.05)。与轻度组比较,中-重度组GLPSS、GLPSSr、GRPSS、GRPSSr均减低,差异有显著性(F=4.25~42.52,P<0.05)。结论主动脉瓣狭窄早期,左心室GLPSS、GLPSSr减低,随着疾病进展出现GRPSS、GRPSSr的减低。

Objective To investigate the changes in left ventricular longitudinal strain and radial strain and strain rates in patients with aortic stenosis by velocity vector imaging（VVI）. Methods Fifty-five aortic stenosis patients with normal left ventricular ejection fraction were divided into mild group（25cases）and moderate-to-severe group（30cases）according to the degree of aortic stenosis.Twenty-five healthy age-and sex-matched volunteers were selected as the control group.VVI was used to measure left ventricular global longitudinal peak systolic strain（GLPSS）and GLPSS rate（GLPSSr）,as well as left ventricular global radial peak systolic strain（GRPSS）and GRPSS（GRPSSr）. Results Compared with the control group,the mild group had significantly lower GLPSS and GLPSSr（F=42.52,23.88;P0.01）,while the moderate-to-severe group had significantly lower GLPSS,GLPSSr,GRPSS,and GRPSSr（F=4.25-42.52,P0.01）.There was no significant difference in GRPSS and GRPSSr between the control group and the mild group（P〈0.05）.Compared with the mild group,the moderate-to-severe group showed significant reductions in all the four parameters（F=4.25-42.52,P〈0.05）. Conclusion The left ventricular GLPSS and GLPSSr decrease in the early stage of aortic stenosis,and GRPSS and GRPSSr decrease as the disease progress.