主动脉外科手术后并发急性肾损伤的研究进展

Research progress of acute kidney injury after aortic surgery

急性肾损伤（AKI）是临床常见的危重症，是重症医学及心脏大血管外科手术中较为常见的并发症，严重影响了患者的预后。近年来，随着主动脉外科的迅速发展，AKI的发生率比过去明显升高，术后AKI的发生明显增加了患者的病死率。因此主动脉外科手术后并发AKI的早期诊断和治疗已成为临床亟待解决的难题。本文对主动脉外科手术后并发AKI的机制、AKI诊断及分级标准、相关危险因素、早期诊断的新生物学指标、预防和治疗的研究新进展进行综述，以期为主动脉外科术后并发AKI的早期诊断及治疗提供帮助。

Acute kidney injury （AKI） is a common critical complication in clinical practice of severe medicine and cardiovascular surgery, which has serious effects on prognosis of patients. The incidence of AKI after aortic surgery significantly increases in recent years and leads to more mortality. Early diagnosis and treatment of AKI after aortic surgery have became problems that require urgent solution. This paper reviewed mechanisms, diagnostic and grading criteria, risk factors, biological indicators, methods for prevention and treatment of AKI after aortic surgery.