精准心脏病学:研究到实践

Precision cardiology: From research to practice

精准医学通过整合表型组学、多生物组学及环境社会因素,借助现代信息学技术实现个体化治疗的目标。精准心脏病学将精准医学理念与方法运用于心血管领域,采用大规模、深入型、创新性研究方法实现研究突破,促进药物研发与应用,结合临床对不同遗传背景、环境暴露的个体提出个体化风险评估、疾病诊断和干预方案,进行针对性的心血管疾病预防和诊治,最终改善患者预后并提高患者生活质量。精准心脏病学目前面临着诸多亟待解决的技术、社会和伦理障碍。随着研究与认识的深入,精准心脏病学将在攻克心血管疾病领域的诸多难关、提高心血管疾病的诊治能力过程中发挥重要作用。

With the progress of the modern information technology, the precision medicine, combined with the omics, the phenomics and the social-environmental elements, has achieved the personalized management of the diseases. In the precision cardiology, the concepts and the methods of the precision medicine are applied to the field of cardiovascular diseases, with large-scale, systematic and innovative researches to support the pharmaceutical development, the risk assessment, the disease diagnosis and the management, leading eventually to the relief of the disease burden and the improvement of the life quality. Meanwhile, the development of the precision cardiology faces technological, social and ethical challenges. With the advances in researches and clinical applications, the precision cardiology will prove its value in the combat with the cardiovascular diseases and improve the population health.