六钼酸/苄基三乙基氯化铵催化合成氧杂蒽二酮类衍生物

Hexamolybdate/BTEAC Composite Catalyzed Synthesis of Xanthenedione Derivatives

在六钼酸和苄基三乙基氯化铵(BTEAC)的复合催化作用下,以芳香醛为原料,分别与1,3-环己二酮和5,5-二甲基-1,3-环己二酮在乙腈溶剂中,通过缩合反应得到一系列高产率氧杂蒽二酮类衍生物;并在此基础上探讨了合成该类化合物的最佳反应溶剂、最佳催化剂、最佳稳定剂及其用量等,同时验证了该催化体系可重复使用5次而催化活性无明显降低.最后提出了可能的反应机理.

A series of xanthenedione derivatives were efficiently synthesized by condensation reaction from aromatic aldehydes and 1,3-cyclohexanedione or 5,5-dimethyl-1,3-cyclohexane dione which were co-catalyzed by hexamolybdate and benzyl triethyl ammonium chloride （BTEAC）.In addition, the reaction solvent, composite catalyst and its dosage were studied.The catalytic system can be easily separated and reused for up to four times without loss of catalytic activities.The possible reaction mechanism is proposed.