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局部进展期胃癌根治术后同期放化疗与单纯化疗的疗效比较 被引量:1

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摘要 目的比较局部进展期胃癌根治术后同期放化疗与单纯化疗的疗效。方法选取72例局部进展期胃癌患者为研究对象,均在我院接受胃癌根治术,将患者随机分为同期放化疗组和单纯化疗组,每组36例,比较2组的生存率,复发率以及Ⅲ、Ⅳ度不良反应情况。结果同期放化疗组的3 a生存率为75.0%,显著高于单纯化疗组的52.8%(P<0.05)。同期放化疗组2、3 a复发率分别为11.1%、25.0%,均显著低于单纯化疗组的33.3%、52.8%(P均<0.05)。同期放化疗组的Ⅲ、Ⅳ度恶心呕吐,Ⅲ、Ⅳ度腹泻,Ⅲ、Ⅳ度白细胞数减少,Ⅲ、Ⅳ度血小板减少,Ⅲ、Ⅳ度肝功能损伤,Ⅲ、Ⅳ度肾功能受损发生率与单纯化疗组比较,差异无统计学意义(P均>0.05)。结论局部进展期胃癌根治术后同期放化疗可以更好控制患者局部复发率,延长患者的生命,且患者具有较好的耐受性。
出处 《肿瘤基础与临床》 2017年第4期344-346,共3页 journal of basic and clinical oncology
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