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不同牵张力值对其成骨相关因子RUNX2、Osterix表达的影响分析

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摘要 目的探索不同牵张力值对成骨相关因子人牙周膜成纤维细胞核心结合因子(RUNX2)和成骨细胞特异性转录因子(Osterix)表达的影响分析。方法随机选取口腔门诊10~14岁需要拔除的牙,检查所取牙齿标本根尖没有发生病变,牙根正常没有发生骨质吸收,牙周组织无发生炎症性病变。共设定为1个对照组与3个实验组,同时依据加载的时间长短还设定了0 h、6 h、12 h以及24 h 4个时间段。利用SPSS 20.0统计学软件进行分析。结果随着培养和加压时间的延长两种成骨相关因子的积分光密度(IOD)值也呈现逐渐升高趋势,差异有统计学意义(P<0.05);各个时间点动态牵张力A组和B组的两种成骨相关因子IOD值高于对照组,差异有统计学意义(P<0.05);静牵张力组与对照组不同时间点两种成骨相关因子的IOD值差异无统计学意义(P>0.05)。结论牵张力值和作用时间与成骨相关因子RUNX2和Osterix的IOD值存在有明显的正相关性。
作者 李跃 李海清
出处 《继续医学教育》 2017年第8期133-134,共2页 Continuing Medical Education
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