原发性高血压患者血清胱抑素C检测临床意义

Clinical Significance of Measureing Serum Cystatin C Level in Patients With Essential Hypertension

目的探讨原发性高血压患者血清胱抑素C(CysC)检测的临床意义。方法选取原发性高血压患者100例,按是否有心功能不全分为观察组与对照组。分别检测所有患者CysC等指标,进行统计学分析。结果观察组血清CysC水平高于对照组,差异有统计学意义(P<0.05),且CysC水平随NYHA心功能分级的增高而增高,并与LVEF呈显著负相关(r=-0.82,P<0.05)。结论血清CysC在评价原发性高血压患者心功能及预后评估中有重要意义。

Objective To discuss clinical significance of measureing serum cystatin C（CysC） level in patients with essential hypertension.Methods 100 patients with essential hypertension were divided into observation group and control group according to whether or not there was cardiac insufficiency.Respectively,all patients were detected the serum CysC and other indicators,for statistical analysis.Results The serum CysC level was higher than the control group,the difference was statistically significant（P0.05）,and the serum CysC level increased with the increasing of NYHA heart function classification,and LVEF was significantly negative correlation（r=0.82,P0.05）.Conclusion The serum CysC in evaluation of cardiac function in patients with essential hypertension and prognosis assessment has important significance.