期刊文献+

晚期肾细胞癌靶向治疗的临床研究进展 被引量:11

下载PDF
导出
摘要 肾细胞癌(renal cell cancer,RCC)的发病率逐年升高,我国相关的流行病学调查显示国内新发肾癌病例数呈逐年增加。根据《全国肿瘤登记年报》,2009年中国肾癌的发病率为4.5/10万,死亡率为1.46/10万。
出处 《现代泌尿生殖肿瘤杂志》 2017年第3期185-189,192,共6页 Journal of Contemporary Urologic and Reproductive Oncology
  • 相关文献

参考文献3

二级参考文献38

  • 1Motzer R J, Hutson TE, Tomczak P, et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma [ J ]. N Engl J Med, 2007, 356:115-124.
  • 2Escudier B, Eisen T, Stadler WM, et al. Sorafenib in advanced clear-cell renal-cell carcinoma [ J]. N Engl J Med, 2007, 356: 125-134.
  • 3Hammers HI, Verheul HM, Salumbides B, et al. Reversible epithelial to mesenchymal transition and acquired resistance to sunitinib in patients with renal cell carcinoma: evidence from a xenograft study[J]. Mol Cancer Ther, 2010, 9:1525-1535.
  • 4Rini BI. New strategies in kidney cancer: therapeutic advances through understanding the molecular basis of response and resistance[ J]. Clin Cancer Res, 2010, 16 : 1348-1354.
  • 5Busch J, Seidel C, Kempkensteffen C, et al. Sequence therapy in patients with metastatic renal cell carcinoma: comparison of common targeted treatment options following failure of receptor tyrosine kinase inhibitors [ J ]. Eur Urol, 2011, 60 : 1163-1170.
  • 6Houghton PJ. Everolimus [ J]- Clin Cancer Res, 2010, 16: 1368-1372.
  • 7Makhov PB, Golovine K, Kuitikov A, et al. Modulation of Akt./ mTOR signaling overcomes sunitinib resistance in renal and prostate cancer ceils [ J]. Mol Cancer Ther, 2012, 11 : 1510- 1517.
  • 8Di Lorenzo G, Buonerba C, Fedefico P, et al. Third-line sorafenih after sequential therapy with sunitinib and mTOR inhibitors in metastatic renal cell carcinoma[ J]. Eur Urol, 2010, 58:906-911.
  • 9Blesius A, Beuselinck B, Chevreau C, et al. Are tyrosine kinase inhibitors still active in patients treated with metastatic renal cell carcinoma previously treated with a tyrosine kinase inhibitors and everolimus? Experience from 36 patients treated in France in the RECORD-1 Trial[ J]. Clin Genitourin Cancer, 2013, 11 : 128- 133.
  • 10Granwald V, Seidel C, Fenner M, et al. Treatment of everolimus- resistant metastatic renal cell carcinoma with VEGF-targeted therapies[ J 1. Br J Cancer,2011, 105 : 1635-1639.

共引文献13

同被引文献70

引证文献11

二级引证文献50

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部