细胞沉渣石蜡包埋、免疫组织化学染色病理检查对判断浆膜腔积液良恶性的价值分析

Analysis of Value of Diagnosis of Determining Benign or Malignant Serous Effusion Cellular by Sedimentation Paraffin Embedding and Immunohistochemical Staining of Pathological

目的:分析细胞沉渣石蜡包埋联合免疫组织化学染色病理检查对于判断浆膜腔积液良恶性的临床价值。方法:择取2015年1月~2016年2月某院收治的浆膜腔浆膜腔积液患者214例作为研究对象,运用随机数字表将其等分为研究组和参照组,每组107例。参照组患者行单纯细胞沉渣石蜡包埋检查,研究组患者在参照组患者基础上联合实免疫组织化学病理检查,观察比较两组患者的恶性肿瘤细胞检出率以及良恶性肿瘤诊断准确率。结果:研究组患者的恶性肿瘤细胞检出率和良恶性肿瘤肿瘤诊断准确率显著高于参照组,组间数据差异具有统计学意义(P<0.05)。结论:针对浆膜腔积液患者行细胞沉渣石蜡包埋检查联合免疫组织化学染色病理检查,能够显著提升患者的恶性肿瘤细胞检出率和良恶性肿瘤诊断准确率,优化患者的治疗效果和生存质量,值得临床推广。

Objective：To analyze the clinical value of cell sedimentation paraffin embedding combined with immunohistochemical staining for pathological examination of serous effusion.Methods：A total of 214 patients with serosal hydrocele effusion were enrolled in this study from January 2015 to February 2016.The patients were divided into study group and control group by random number table,with 107 cases in each group.In the control group,the patients were treated with paraffin embedding.The patients in the study group were treated with immunohistochemical pathology on the basis of the patients in the control group.The detection rate of malignant tumor cells and the diagnostic accuracy of benign and malignant tumors were observed and compared.Results：The detection rate of malignant tumor cells in the study group and the diagnosis of benign and malignant tumor were significantly higher than those of the reference group,the difference was statistically significant（P〈0.05）.Conclusion：The pathologic examination of cytoremal sediment paraffin combined with immunohistochemical staining can significantly improve the detection rate of malignant tumor cells and the diagnosis of benign and malignant tumors,and optimize the therapeutic effect and quality of life,worthy of clinical promotion.