对比兰索拉唑和奥美拉唑配合抗生素治疗酒精型消化溃疡的临床价值

Comparison of Clinical Value in Treating Alcoholic Digestive Ulcer by Lansoprazole and Omeprazole Combined with Antibiotics

目的:对比分析采用兰索拉唑和奥美拉唑配合抗生素治疗酒精型消化溃疡的临床有效性。方法:取2015年3月~2016年3月某院收治的酒精型消化溃疡72例,分为两组,A组用兰索拉唑配合抗生素治疗,B组用奥美拉唑配合抗生素治疗,对比两组治疗效果。结果:A组治疗后腹痛消失时间优于B组,P<0.05;A组治疗后不良反应发生率、总有效率、复发率分别为5.56%、94.44%、2.78%,优于B组的16.67%、77.78%、19.44%,P<0.05。结论:与奥美拉唑配合抗生素治疗酒精型消化溃疡的效果相比,采用兰索拉唑配合抗生素治疗的疗效更为显著,值得推广。

Objective：To compare the clinical efficacy of lansoprazole and omeprazole in the treatment of alcoholic digestive ulcer with antibiotics.Methods：From March 2015 to March 2016,72 cases of alcohol digestive ulcer were divided into two groups.Group A was treated with lansoprazole with antibiotics.Group B was treated with omeprazole and antibiotics.Then compare the treatment effect of the two groups.Results：The time of disappearance of abdominal pain in group A was better than that in group B（P〈0.05）.The incidence of adverse reactions,total effective rate and recurrence rate in group A were 5.56%,94.44% and2.78%,respectively,which were better than those in group B %,77.78%,19.44%,P〈0.05.Conclusion：Compared with the efficacy of omeprazole combined with antibiotics in the treatment of alcoholic digestive ulcer,the efficacy of lansoprazole combined with antibiotics was more significant and worthy of promotion.