右美托咪定在妇科腹腔镜手术麻醉中的应用

Application of Dexmedetomidine in Gynecological Laparoscopic Anesthesia

目的:分析右美托咪定在妇科腹腔镜手术静脉吸入复合全麻中的价值。方法:选择2016年1月~2017年1月某院收治的128例行妇科手术者为研究对象,将其分为两组,每组64例。麻醉方式均为静脉吸入复合全麻,观察组患者气管插管诱导前10min静脉泵注浓度为0.5μg/kg的右美托咪定,对照组使用相同方式泵注10ml 0.9%NS溶液。结果:相较于用药前,观察组患者的各时间段心率以及血压均无显著变化,P>0.05;在建立气腹后到30min时,上述指标均比对照组低;用药后10min~气腹后30min,观察组的BIS分数、Ramsay分数镇静、拔管时长、呼吸恢复时长、定向力恢复时长、唤醒时长、住院时间、不良反应率低于对照组,P<0.05。结论:对接受腹腔镜手术的妇科疾病患者,将右美托咪定作为麻醉辅助用药,镇静效果好,血流动力学稳定。

Objective：To analyze the value of dexmedetomidine in the combined general anesthesia of gynecological laparoscopic surgery.Methods：From January 2016 to January 2017,128 patients undergone gynecological surgery were divided into two groups（n=64）.Anesthesia was intravenous inhalation combined with general anesthesia,the observation group was intravenously injected with 0.5μg/kg dexmedetomidine10 min before tracheal intubation,and the control group using the same way to pump 10ml0.9% NS solution.Results：Compared with before using injects,the heart rate and blood pressure of the patients in the observation group did not change significantly（P〈0.05）.After the establishment of pneumoperitoneum,30 min later,the above indicators of the observation group were lower than those of the control group 10 min.The BIS scores,Ramsay scores,duration of extubation,duration of respiration recovery,duration of rejuvenation,duration of awakening,hospitalization time and adverse reaction rate were lower than those in control group at 30 min after treatment（P〈0.05）.Conclusion：For laparoscopic surgery in patients with gynecological diseases,the auxiliary use of Dexmedetomidine has sedative effect with stable hemodynamic.