胎盘蛋白13在晚期自然流产孕妇血清中的表达及意义
摘要
晚期自然流产是指由自然因素导致的妊娠时间大于12周不足28周,且胎儿体重不足1 000 g而终止妊娠者。胚胎着床后31%发生自然流产,其中80%为早期流产[1]。晚期流产最常发生于妊娠18~25周,通常表现为阴道流血,不规则下腹痛,腰酸及下坠感等症状,
出处
《上海预防医学》
CAS
2017年第8期625-627,共3页
Shanghai Journal of Preventive Medicine
基金
上海市宝山区科委项目(13-E-11)
二级参考文献11
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1Spencer K,Cowans N J,Chefetz I,et al.First-trimester maternal serum PP13,PAPP-A and second trimester uterine artery DoPPler pulsatility index as markers of pre-eclampsia[J].Ultrasound Obstet Gynecol,2007,29(2):128-134.
-
2Sekizawa A,Purwasunu Y,Yashimura S,et al.PP13 mRNA expression in trophoblasts from preeclamptic placentas[J].Reproductive Sciences,2009,16(4):408.
-
3Than N G,Romero R,Hillermann R,et al.Prediction of preeclampsia-a workshop report[J].Placenta,2008,29(A):83-85.
-
4Khalil A,Cowans N J,Spencer K,et al.First trimester maternal serum placental protein 13 for the prediction of pre-eclampsia in women with a priori high risk[J].Prenat Diagn,2009,29(8):781-789.
-
5Shimizu H,Sekizawa A,Purwasunu Y,et al.PP13 mRNA expression in the cellular component of maternal blood as a marker for preeclampsia[J].Prenat Diagn,2009,29(13):1231-1236.
-
6Romero R,Kusanovic J P,Than N G,et al.First-trimester maternal serum PP13 in the risk assessment for preeclampsia[J].Am J Obstet Gynecol,2008,199(2):122.
-
7Chafetz I,Kuhnreich I,Sammar M,et al.First-trimester placental protein 13 screening for preeclampsia and intrauterine growth restriction[J].Am J Obstet Gynecol,2007,197(1):35.e1-e7.
-
8Dugoff L,Lynch A M,Hobbins J C,et al.First trimester uterine artery doppler abnormalities predict subsequent intrauterine growth restriction[J].Am J Obstet Gynecol,2005,193(3):1208-1212.
-
9Nicholas S S,Stamilio D M,David M,et al.Predicting adverse neonatal outcomes in fetuses with abdominal wall defects using prenatal risk factors[J].Am J Obstet Gynecol,2009,201(4):383.e1-e6.
-
10Cowans N J,Spencer K,Meiri H.First-trimester maternal placental protein 13 levels in pregnancies resulting in adverse outcomes[J].Prenat Diagn,2008,28(2):121-125.