丙型肝炎患者HPA多态性与血小板计数的关系

Relationship between human platelet antigen polymorphism and platelet count in patients with HCV infection

目的:研究丙型肝炎患者血小板抗原(HPA)多态性与血小板计数的相关性。方法:对丙型肝炎患者进行HPA-2、-3、-5和HPA-15基因分型及血小板计数。结果:不同HPA基因型的丙型肝炎患者,其血小板计数差异无统计学意义。结论:HPA多态性与丙型肝炎患者血小板计数无相关性。

Objective：To evaluate the relationship between human platelet antigen（HPA）polymorphism and platelet count in the patients with HCV infection.Method：We genotyped the polymorphisms of HPA-2,-3,-5and-15 in the patients with HCV infection.Result：Platelet count had no difference among HPA-2,-3,-5or HPA-15 polymorphisms.Conclusion：There may be no relationship between HPA polymorphisms and platelet count in the patients with HCV infection.