新生儿双通道快速同步换血术的临床研究

Clinical study of double channel fast synchronous exchange transfusion in neonates

目的 :探讨新生儿双通道快速同步换血术的临床效果。方法 :收集2013年10月至2016年10月收治的新生儿重症高胆红素血症患儿34例,给予双通道快速同步换血术治疗,观察换血后患儿相关血液指标的变化情况。结果:换血后2h,患儿总胆红素、直接胆经素和间接胆红素浓度均显著低于入院时(P<0.05);白细胞计数、血小板计数、pH值、K+浓度均显著低于入院时,红细胞计数Ca^(2+)浓度均显著高于入院时(P<0.05)。结论 :双通道快速同步换血术能够有效改善新生儿重症高胆红素血症患儿的胆红素和血常规指标,值得临床推荐。

Objective： To explore the clinical effect of double channel fast synchronous exchange transfusion in neonates. Methods： From October 2013 to October 2016, 34 neonates with severe hyperbilirubinemia were collected and treated with double channel fast synchronous exchange transfusion and the changes of blood indexes in children after exchange transfusion were observed. Results： After exchange transfusion of 2 h, total bilirubin, direct bilirubin and indirect bilirubin concentrations were significantly lower than those on admission （P〈0.05）. White blood cell count, platelet count, pH value and K＋ concentration were significantly lower than those on admission, and red blood cell count and Ca〉 concentration was significantly higher than those on admission （P〈0.05）. Conclusion： Double channel fast synchronous exchange transfusion can effectively improve bilirubin and blood routine indexes in neonates with severe hyperbilirubinemia, which is worthy of clinical application.