血流感染者鲍曼不动杆菌耐药性分析

Drug resistance of acinetobacter baumannii in bloodstream infection cases

目的对本院的鲍曼不动杆菌血流感染者进行临床特征及耐药性分析,为临床有效治疗提供有利证据。方法 23例血流感染者共检测出74株鲍曼不动杆菌,通过纸片扩散法检测鲍曼不动杆菌耐药性。结果 23例鲍曼不动杆菌血流感染者中,心脑血管疾病11例,糖尿病12例。头孢曲松钠、头孢唑啉钠、头孢他啶耐药率最高,分别为39.19%、21.62%、21.62%,其次为阿奇霉素、克林霉素、氧氟沙星,耐药率分别为17.57%、13.51%、13.51%,耐药率分析最低的青霉素液为0。结论鲍曼不动杆菌的血流感染者中的耐药性分析已明确,对于药物的有效选择起到了重要的作用。

Objective To analyze the clinical characteristics and drug resistance of acinetobacter baumannii bloodstream infection patients, to provide favorable evidence for the effective treatment. Methods Clinical data of 23 cases of bloodstream infection by screening of 74 strains of acinetobacter baumannii was retrospectively analyzed, and paper diffusion method was used for drug susceptibility test. Results Among 23 acinetobacter baumannii bloodstream infection patients, there were 11 cases of cardio-cerebrovascular disease and 12 cases of diabetic mellitus. Ceftriaxone sodium, cefazolin sodium, ceftazidime had the highest resistance rate respectively as 39.19%, 21.62% and 21.62%, followed by azithromycin, clindamycin, ofloxacin, with resistance rates respectively as 17.57%, 13.51%, 13.51%, and The lowest resistance rates of penicillin solution was 0. Conclusion The drug resistance analysis in patients with acinetobacter baumannii bloodstream infection has been clear and it has played an important role in the effective selection of drugs.