64例银杏达莫注射液不良反应分析

Analysis of Adverse Reactions in 64 Cases of Yinxingdamo Injection

目的通过对银杏达莫注射液不良反应的分析,为该药品临床合理用药奠定良好基础。方法通过回顾性分析方法,对我院2012年4月—2015年4月共64例银杏达莫注射液不良反应病例进行分析。结果银杏达莫注射液的不良反应,主要体现在神经系统、消化系统、皮肤的损坏以及过敏样反应。患者出现药物不良反应(ADR)的时间在输液后2 min^5 d,在输液10 min内、10~30 min、30 min^2 h不良反应发生例数最多;发生神经系统反应的有23.44%、消化系统反应9.38%、心血管系统反应6.25%、皮肤及附件4.69%、全身性损害类型3.13%。结论银杏达莫注射液药品成分多且制取工艺杂,为了保证其用药疗效,加强监控其临床不良反应尤为重要。

Objective Through the analysis of the adverse reactions of yinxingdamo injection, it can lay a good foundation for the rational use of drugs in the clinic. Methods Through retrospective analysis, we analyzed 64 cases of adverse reactions of yinxingdamo injection in our hospital from April 2012 to April 2015. Results The adverse effects of yinxingdamo injection were mainly manifested in the nervous system, digestive system, skin damage, and allergic reactions. The time of occurrence of ADR in patients was 2 min to 5 d after infusion, and there were most adverse reactions in 10 min, 10~30 min and 30 min to 2 h; The nervous system response was 23.44%, digestive system reaction 9.38%, cardiovascular system reaction 6.25%, skin and accessories 4.69%, systemic damage type 3.13%. Conclusion It is very important to strengthen the monitoring of the adverse drug reactions of yinxingdamo injection.