三联疗法治疗宫缩乏力性产后出血疗效观察

Clinical observation of triple therapy for postpartum hemorrhage due to uterine inertia

目的观察三联疗法治疗宫缩乏力性产后出血的临床疗效。方法选取我院收治的184例宫缩乏力性产后出血患者,随机对照组和观察组,各92例。对照组给予常规治疗,观察组给予三联疗法(缩宫素+麦角新碱+卡前列素氨丁三醇)治疗,比较两组患者治疗后不同时期出血量、休克情况以及临床疗效。结果观察组用药后2、24 h出血量和平均出血量显著少于对照组(P<0.05)。治疗过程中,两组中度休克发生率比较,差异无统计学意义(P>0.05);观察组代偿性休克发生率高于对照组,轻度、重度休克发生率低于对照组(P<0.05)。治疗后,观察组患者总有效率高于对照组(P<0.05)。结论三联疗法(缩宫素+麦角新碱+卡前列素氨丁三醇)治疗宫缩乏力性产后出血有良好的临床疗效。

Objective To observe the clinical effect of triple therapy for postpartum hemorrhage due to uterine inertia. Methods One hundred and eighty-four cases of patients with postpartum hemorrhage due to uterine inertiain in our hospital were randomly divided into control group and observation group, with 92 cases in each group. The control group was treated with conventional therapy, while the observation group was treated with triple therapy （oxytocin ＋ ergometrine ＋carboprost tromethamine）. The amount of bleeding at different times after treatment, situation of shock and clinical efficacy in the two groups were compared. Results The amount of bleeding at 2 and 24 h after treatment and the average amount of bleeding in the observation group were significantly lower than those in the control group （P〈0.05）. There was no significant difference in the moderate shock rate between the two groups （P〉0.05）; the compensatory shock rate in the observation group was higher than that in the control group, and the mild and severe shock rate were less than those of the control group （P〈0.05）. After treatment, the total effective rate of the observation group was higher than that of the control group （P〈0.05）. Conclusion Triple therapy （oxytoein ＋ ergometrine ＋ carboprost tromethamine） in the treatment of postpartum hemorrhage due to uterine inertia has a good clinical effect.