彩色多普勒超声筛查孕中晚期筛查胎儿畸形的价值研究

The value of color Doppler ultrasonography in screening fetal malformation in the middle and late pregnancy

目的探讨彩色多普勒超声筛查孕中晚期筛查胎儿畸形的价值研究。方法选自我院于2016年1月至2016年12月期间进行产前检查中孕中晚期产妇2784例。采用彩色多普勒超声诊断仪,探头频率为2.5MHz至5.0MHz。取孕妇侧卧位或者仰卧位,行多方位详细检查。结果本组中孕中晚期产妇2784例产前检出胎儿畸形40例。其中心脏畸形9例、脑积水5例、无脑儿4例、唇、腭裂2例、脊椎畸形8例、四肢畸形9例、泌尿道畸形3例;本组40例胎儿畸形中,漏诊5例,包括心脏畸形2例、脊椎畸形2例、四肢畸形1例;心脏畸形与妊娠结局符合率为77.78%,脑积水与妊娠结局符合率为100.00%,无脑儿与妊娠结局符合率为100.00%,唇、腭裂与妊娠结局符合率为100.00%,脊椎畸形与与妊娠结局符合率为75.00%,四肢畸形与妊娠结局符合率为97.50%,泌尿道畸形与妊娠结局符合率为100.00%。畸形胎儿与妊娠结局符合率为87.50%。结论彩色多普勒超声筛查能够有效地筛查孕中晚期胎儿畸形,且可作为一种妊娠早期漏诊的检查手段,为临床诊断胎儿畸形提供参考价值。

Objective：To investigate the value of color Doppler ultrasonography in screening fetal malformation in the middle and late pregnancy. Methods：From January 2016 to December 2016 in our hospital during the prenatal examination of 2784 cases of advanced maternal. Using color Doppler ultrasound diagnostic instrument,probe frequency of 2.5 MHz to 5 MHz. Take a pregnant woman lying on the side or supine position,multi-directional detailed inspection. Results：In this group,2784 cases of prenatal fetal malformation were detected in the middle and late stage of pregnancy in this group（n=40）. The cardiac malformation in 9 cases,5 cases of hydrocephalus,4 cases of anencephaly,2 cases of cleft lip and palate,8 cases of spinal deformity,9 cases of limb deformities,3 cases of urinary tract malformation;40 cases of this group of fetal malformation,5 cases of misdiagnosis,including heart malformation in 2 cases,2 cases of limb deformities,spinal deformity 1 cases of cardiac malformations and pregnancy outcome;the coincidence rate is 77.78%,hydrocephalus and pregnancy outcomes the coincidence rate is 100%,anencephaly and pregnancy outcomes the coincidence rate is 100%,and the pregnancy outcome of cleft lip and palate coincidence rate was 100%,and vertebral deformity and pregnancy outcome coincidence rate was 75%,limb deformities and pregnancy outcome coincidence rate was 97.50% urinary tract abnormalities and pregnancy outcome,the coincidence rate is 100%. The coincidence rate of fetal malformation and pregnancy outcome was 87.50%. Conclusion：Color Doppler ultrasound screening can effectively screening for fetal abnormalities in the middle and late pregnancy,and can be used as a means of early pregnancy missed diagnosis,provide a reference value for the clinical diagnosis of fetal malformations.