门冬氨酸钾镁联合胺碘酮对急性心肌梗死并发室性心律失常的疗效及安全性

Analysis on the efficacy and safety of acute myocardial infarction complicated with ventricular arrhythmia in patients with potassium aspartate magnesium combined with amiodarone

目的探讨门冬氨酸钾镁联合胺碘酮对急性心肌梗死并发室性心律失常的疗效和安全性。方法选取2015年2月-2016年3月本院收治急性心肌梗死并发室性心律失常患者94例,随机分为观察组和对照组各47例。对照组患者给予胺碘酮治疗,观察组患者在对照组基础上加用门冬氨酸钾镁治疗,对比两组治疗效果及用药安全性。结果观察组总有效率为95.74%(45/47),显著高于对照组的80.85%(38/47),差异有统计学意义(P<0.05)。两组皮疹、房室传导阻滞及其他不良反应发生率对比,差异均无统计学意义(均P>0.05)。结论门冬氨酸钾镁联合胺碘酮对急性心肌梗死并发室性心律失常患者疗效显著,安全性较好。

Objective To study the effect of potassium aspartate magnesium combined with amiodarone on acute myocardial infarction complicated with ventricular arrhythmia patients and to analyze its security. Methods From February 2015 to March 2016,94 cases of patients with acute myocardial infarction complicated with ventricular arrhythmia in our hospital were selected,the digital method was randomly divided into observation group and control group,each of 47 cases. The control group were treated with amiodarone therapy,patients in the observation group was treated with Potassium Aspartate magnesium on the basis of control group,compared two groups of curative effect and safety of drugs.Results The total effective rate of the observation group was 95.74%（ 45/47）,which was significantly higher than that of the control group of80.85%（ 38/47）,the difference was statistically significant（ P 0. 05）. There was no significant difference in the incidence of rash,atrioventricular block and other adverse reactions between the two groups,and the difference was not statistically significant（ P〉0.05）.Conclusion The curative effect of potassium aspartate magnesium combined with amiodarone on acute myocardial infarction complicated with ventricular arrhythmia are significant,with good safety.