高血压脑出血患者术后实施镇痛镇静治疗的临床效果

The Clinical Effect of Sedation Analgesia Treatment in Patients with Hypertensive Intracerebral Hemorrhage after Operation

探讨高血压脑出血术后镇痛镇静治疗的临床疗效。将218例高血压脑出血患者随机分为两组,试验组患者术后应用舒芬太尼+地佐辛+咪达唑仑镇痛镇静,对照组单纯应用咪达唑仑,观察两组治疗效果。试验组患者术后镇静-躁动评分、血压达危险值例数、颅内压监测值、72h的NIHSS值、48h内再出血率、7d病死率、不良反应发生率均明显低于对照组,差异均有统计学意义(P<0.05)。高血压脑出血患者开颅术后应用舒芬太尼+地佐辛+咪达唑仑镇痛镇静,可减少患者术后躁动,稳定血压及颅内压,保护神经功能,降低颅内再出血率、病死率、不良反应发生率,值得临床应用和推广。

To study clinical effect of sedation analgesia treatment in patients with hypertensive intracerebral hemorrhage after operation.218 patients with hypertensive cerebral hemorrhage were randomly divided into two groups, Sufentanil＋Dezocine＋Midazolam had been applied to postoperative sedation analgesia treatment in experiment group, the control group used midazolam only, to observe the therapeutic effect of two groups.The sedation-agitation score, the number of patients with dangerous blood pressure, intracranial pressure, national institutes of health stroke scale of postoperative 72h, rebleeding rate within 48h, 7 days＇mortality and adverse reaction of experimental group were all lower than control group, the difference had statistical significance （P〈0.05）.In patients with hypertensive intracerebral hemorrhage after operation, sufentanil＋dezocine＋midazolam could reduce postoperative dysphoria, stabilize postoperative blood pressure and ICP, protect neurological function, meanwhile, reduce the rebleeding rate, mortality and adverse reaction.It is worth clinical application and promotion.