摘要
抗酒石酸酸性磷酸酶(type 5 acid phosphatase/tartrate-resistant acid phosphatase,ACP5/TRACP/TRAP)是酸性磷酸酶家族中的金属蛋白酶,是骨吸收和破骨细胞活性的良好标志物.近来发现ACP5在多种肿瘤中的表达比配对正常组织中的表达显著上调,该现象提示,ACP5可能肿瘤的发生发展中起到一定的作用.
The acid phosphatase 5, tartrate resistant or tartrate-resistant acid phosphatase（ACP5/TRACP/TRAP） is a metalloproteinase of the acid phosphatase family, which is a good marker of bone resorption and osteoclast activity. It has recently been found that the expression of ACP5 in a variety of tumors is significantly higher than that in matched normal tissues. These suggest that ACP5 may play an important role in the occurrence and development of tumors.
出处
《世界华人消化杂志》
CAS
2017年第23期2133-2138,共6页
World Chinese Journal of Digestology
基金
嘉兴市科技基金资助项目
No.2016AY23043
嘉兴市第一医院"启明星"计划基金资助项目
No.2017QMX001~~
关键词
抗酒石酸酸性磷酸酶
肝癌
胃癌
胆囊癌
乳腺癌
骨转移
ACP5
Hepatic carcinoma
Gastric carcinoma
Gallbladder carcinoma
Breast cancer
Bone metastasis
