心率变异性分析在青年高血压靶器官损伤患者的诊疗意义

Heart Rate Variability Analysis in Diagnosis and Treatment of Hypertensive Target Organ Damage in Young Patients

目的:研究心率变异性(HRV)分析对青年高血压靶器官损伤患者的诊疗意义。方法:选取我院收治的青年高血压患者100例,依据患者是否伴发其他病症、器官损伤等因素,将入选患者划分为观察A组及观察B组各50例,观察A组患者为原发性高血压伴靶器官损伤组,观察B组为单纯原发性高血压组,选取同期于我院体检健康体的青年50例设为对照组进行对照研究;入选3组均进行24h动态生命体征以及心电图监测,对其相关指标变化情况进行对比分析。结果:观察A、B组SDNN、TRIA、SDNN5、PNN50明显低于对照组(P<0.05);观察A组SDNN、SDNN5、TRA、SDANN明显低于观察B组(P<0.05);观察B组各项心率变异性指标明显低于对照组(P<0.05);观察A、B组间PNN50比较统计学差异(P>0.05)。结论:应用HRV分析可对青年高血压靶器官损害患者病情进行及早诊断,有助于提升临床疗效。

Objective： To explore the significance of heart rate variability（ HRV） analysis in diagnosis of target organ damage in young patients with hypertension. Methods： A total of 100 young patients with hypertension admitted in our hospital were included in the study and divided into the observation A group and observation B group with 50 cases in each group according to whether being accompanied by other diseases or organic damage. The patients in the observation A group had primary hypertension accompanied by organic damage,while the patients in the observation B group had pure primary hypertension. A total of 50 young people who came for physical examination were served as the control group. 24 h dynamic vital signs and ECG monitoring were performed for patients in the three groups. The changes of related indicators were compared and analyzed. Results： SDNN,TRIA,SDNN5,and PNN50 in the observation A and B groups were significantly lower than those in the control group（ P〈0.05）. SDNN,SDNN5,TRA,and SDANN in the observation A group were significantly lower than those in the observation B group（ P〈0.05）. HRV indicators in the observation B group were significantly lower than those in the control group（ P〈0.05）. The comparison of PNN50 between the observation A and B groups was not statistically significant（ P〉0.05）. Conclusion： Application of HRV analysis can make an early diagnosis of target organ damage in young patients with hypertension,and contribute to enhance the clinical efficacy.