痛性桥本甲状腺炎35例临床分析

Clinical Analysis of 35 Cases with Painful Hashimoto's Thyroiditis

回顾性分析2009年1月~2016年3月期间35例痛性桥本甲状腺炎患者的临床资料。甲状腺球蛋白抗体、甲状腺过氧化物酶抗体均明显升高,91.4%红细胞沉降率和/或C反应蛋白升高,摄碘率变化不定,25例大量淋巴细胞浸润,11例不同程度纤维化,8例少量多核巨细胞。痛性桥本甲状腺炎是以疼痛和发热为特征的变异性桥本甲状腺炎,确诊有赖于病理。糖皮质激素对多数患者有效,手术切除亦是治疗本病的有效方法。甲状腺功能减退症发生率较高,需密切随访。

Clinical data was retrospectively analyzed in 35 cases of painful Hashimoto＇s thyroiditis from January of 2009 to March of 2016.All have a high titers of thyroid peroxidase antibody and thyroid globulin antibody.91.4% of the cases showed elevated ESR and/or CRP.Radioactive iodine value varies.Histological examination： 25 cases showed a large number of lymphocyte.11 cases present different degrees of fibrosis while 8 cases present a few multinuclear giant cells.Painful Hashimoto＇s thyroiditis is a variation of Hashimoto＇s thyroiditis characterized by thyroid pain and fever.Diagnose depends on pathological results.Glucocorticoid is effective for most patients and operation is also an effective method.Rate of hypothyroidism is high so follow-up is necessary.