液固核磁实验创建模式及管理差异性探讨

Discussion on Differences of Experiment Creation Mode and Management of Liquid NMR and SSNMR

液体核磁与固体核磁在仪器结构配件、样品性质、实验创建模式以及日常管理4个方面存在差别。科研人员需要深入了解二者差别,并且能够根据每个样品自身性质来选择检测要求及校准相应参数。二者在很多方面也有相同点,例如调谐目的、变温实验self-tune以及谱图处理等。总体来说,固体核磁在检测要求及参数校准方面要比液体核磁复杂,每个样品都要根据自身性质来校准参数及选择检测要求。另外,液体样品的各向异性相互作用可以被分子的布朗运动平均掉,但在固体样品中,这些分子运动受限,速度很慢,因此,固体核磁实验需要将样品整体转动来模拟液体样品中的分子运动,以此来消除样品的各向异性相互作用。科研人员必须了解液体和固体核磁的这些特性,才能在日常检测及管理中更好地为教学及科研服务。

There are differences in four aspects of liquid NMR and SSNMR, such as instrument structure and accessories,nature of sample,experiment creation mode and daily management. Researchers are able to select testing requirements and calibrate corresponding parameters according to properties of each sample if they understand these differences. There are also many similarities in both NMRs, for example, tuning purpose, self-tune of variable temperature experiments,spectra processing and so on. Generally,testing requirements and parameters calibration of SSNMR are much more complex than liquid NMR. Each sample of SSNMR has to choose testing requirements and calibrate corresponding parameters according to its properties. Besides,anisotropic interaction of liquid samples can be averaged by the brown motion of molecule,but molecular motion is limited and motion speed is slow in solid samples.Therefore,solid-state samples need to rotate as a whole to simulate molecular motion of liquid samples in order to eliminate the anisotropy of solid-state samples. Researchers can serve teaching and scientific research much better in testing and daily management if they master characteristics of liquid NMR and SSNMR.