226例胸腔镜治疗非小细胞肺癌的临床疗效观察

Clinical effect of 226 cases of thoracoscope on nonsmall-cell lung cancer

目的:研究胸腔镜治疗226例非小细胞肺癌的临床疗效。方法:选取2013年12月至2016年12月在我院治疗的226例非小细胞肺癌病人,随机分为观察组和对照组,每组113例。对照组患者采用传统开胸肺叶切除术和系统性淋巴结清扫术;观察组患者采用胸腔镜辅助肺叶切除术和系统性淋巴结清扫术进行手术治疗。对手术时间、术中出血量、术中清扫淋巴结数,术后胸腔引流量、术后疼痛、并发症发生率以及住院时间进行观察评估。结果:与对照组比较,观察组手术时间较长、术中出血量较少(P<0.05),观察组和对照组淋巴结清扫数目无统计学差别(P>0.05)。观察组和对照组术后疼痛评分、术后胸腔引流量和住院时间等术后指标,均有显著性差别(P<0.05)。观察组和对照组的并发症发生率分别为4.4%和7.7%(P<0.05)。结论:胸腔镜手术治疗非小细胞肺癌具有创伤小、术中失血量少、术后引流量少、术后并发症少、住院时间短、术后恢复快等优势。

Objective：To study the clinical effect of 226 cases of thoracoscope on nonsmall-cell lung cancer.Methods：Two hundred and twenty-six patients with nonsmall-cell lung cancer from December,2013 to December,2016 in The First People Hospital of Zhaotong were randomly divided into observation group（113 cases）and control group（113 cases）.The patients of the control group were treated with traditional open chest lobectomy and systematic lymph node dissection.The patients of the observation group were treated with thoracoscope chest lobectomy and systematic lymph node dissection.The operation time,intraoperative blood loss,the number of lymph nodes removed during operation,the postoperative thoracic drainage,postoperative pain and length of stay in hospital were observed and evaluated.Results：The operation time of observation group was longer and the intraoperative blood loss of observation group was less than that of control group（P〈0.05）.The number of lymph nodes removed during operation of observation group and control group were not different（P〉0.05）.There were significant difference of the postoperative pain,the postoperative thoracic drainage and length of stay in hospital of observation group between observation group and control group（P〈0.05）.The incidence of complications of observation group and control group were 4.4% and 7.7%（P〈0.05）.Conclusion：Treatment of nonsmall-cell lung cancer with thoracoscope demonstrated advantages on trauma,intraoperative blood loss,postoperative thoracic drainage,complications,length of stay in hospital and recovery.